Hydrolysis of N -Sulfinylamines and Isocyanates: A Computational Comparison
✍ Scribed by Ivanova, Elena V.; Muchall, Heidi M.
- Book ID
- 120184855
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 213 KB
- Volume
- 111
- Category
- Article
- ISSN
- 1089-5639
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## Abstract The ^15^N NMR spectra of ten isocyanates, four isothiocyanates, and four __N__‐sulfinylamines have been obtained at the natural‐abundance level by high‐resolution NMR spectroscopy. The results show that isocyanates and isothiocyanates have ^15^N chemical shifts over 200 ppm toward highe
## Abstract Subcutaneous administration of the LD~50~ dose of methyl isocyanate (MIC) to rats induced severe hyperglycaemia, lactic acidosis and uraemia in rats. Neither methylamine (MA) nor N,N′‐dimethylurea (DMU), the hydrolysis products of MIC, administered in equimolar doses had any influence o