Theoretical Evaluation of the Substrate-
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Nathalie Iché-Tarrat; Manuel Ruiz-Lopez; Jean-Claude Barthelat; Alain Vigroux
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Article
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2007
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John Wiley and Sons
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English
⚖ 362 KB
👁 1 views
## Abstract Quantum chemistry methods coupled with a continuum solvation model have been applied to evaluate the substrate‐assisted catalysis (SAC) mechanism recently proposed for the hydrolysis of phosphate monoester dianions. The SAC mechanism, in which a proton from the nucleophile is transferre