## Abstract Selective incorporation of deuterium by platinum‐catalyzed exchange for six ribonucleosides and two 2′‐deoxyribonucleosides has been studied as a function of catalyst/substrate ratio, temperature, time and concentration. In addition to exchange of carbon‐bound hydrogens in purines, pyri
Hydrogenolysis and deuterium exchange of C3 and C4 primary alkylamines catalyzed by platinum films
✍ Scribed by Simon R. Bockett; John L. Brownlees; Gregory N. McPeak; Sharon Millar; S.R. Logan
- Book ID
- 113180137
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 275 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0021-9517
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## Abstract An efficient protocol for the one‐pot reaction of isatoic anhydride (=1,2‐dihydro‐4__H__‐3,1‐benzoxazine‐2,4‐dione), primary alkylamines, and heterocumulenes (isothiocyanates and isocyanates) in H~2~O catalyzed by magnetically recoverable Fe~3~O~4~ nanoparticles is described.
The hydrogen-isotope labeling of nucleic acid bases is sometimes required in nucleic acid research. Many papers have already appeared on deuteration of E-H in purines 2,3) and of 5-H in pyrimidines 4-6) through the ionic exchange processes. This paper describes catalytic hydrogen exchange of nucleos