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Hydrogen–deuterium exchange strategy for delineation of contact sites in protein complexes

✍ Scribed by H. Jane Dyson; Milka Kostic; Jeff Liu; Maria A. Martinez-Yamout


Book ID
113620727
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
969 KB
Volume
582
Category
Article
ISSN
0014-5793

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## Abstract The experimental investigation of site‐specific intra‐ionic hydrogen/deuterium (H/D) exchange in the low‐energy collision‐induced dissociation (CID) product ion spectra of protonated small molecules generated by electrospray ionisation (ESI) is presented. The observation of intra‐ionic