Probing the Non-covalent Structure of Pr
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Smith, David L.; Deng, Yuzhong; Zhang, Zhongqi
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Article
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1997
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John Wiley and Sons
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English
β 403 KB
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The rates at which hydrogens located at peptide amide linkages in proteins undergo isotopic exchange when a protein is exposed to depend on whether these amide hydrogens are hydrogen bonded and whether they are D 2 O accessible to the aqueous solvent. Hence, amide hydrogen exchange rates are a sensi