Hydrogen/deuterium exchange mass spectrometry and optical spectroscopy as complementary tools for studying the structure and dynamics of a membrane protein

Hydrogen-deuterium exchange in membrane

Hydrogen-deuterium exchange in membrane proteins monitored by IR spectroscopy: A new tool to resolve protein structure and dynamics

✍ C. Vigano; M. Smeyers; V. Raussens; F. Scheirlinckx; J.M. Ruysschaert; E. Goorma 📂 Article 📅 2004 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 139 KB 👁 1 views

## Abstract As more and more high‐resolution structures of proteins become available, the new challenge is the understanding of these small conformational changes that are responsible for protein activity. Specialized difference Fourier transform infrared (FTIR) techniques allow the recording of si