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Hydrogen peroxide induced responses of cat tracheal smooth muscle cells

✍ Scribed by V Bauer; M Oike; H Tanaka; R Inoue; Y Ito


Book ID
110002991
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
426 KB
Volume
121
Category
Article
ISSN
0007-1188

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Lysyl oxidase (LO), an enzyme secreted by vascular smooth muscle cells (VSMC), initiates the covalent crosslinking of polypeptide chains within collagen and elastin. The present study reveals that purified LO strongly induces directional migration of VSMC in an in vitro assay system. LO-dependent ch