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Hydrogen Bonding and Attenuation of the Rate of Enzymic Catalysis

✍ Scribed by Li, Zhi-Hong; Bulychev, Alexey; Kotra, Lakshmi P.; Massova, Irina; Mobashery, Shahriar


Book ID
126429017
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
78 KB
Volume
120
Category
Article
ISSN
0002-7863

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On the rate constant of enzyme catalysis
✍ S. Svirschevsky; M. Apostol πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 English βš– 396 KB

A direct calculation is reported of the rate constant of enzyme catalysis within the perturbative approach to the two-level model of enzyme-substrate complex. A simple dependence of the rate constant on the small amplitudes of the permanent, static distortion mode is obtained, whose relevance for th