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Hydrogen-bond basicity of secondary and tertiary amides, carbamates, ureas and lactams

✍ Scribed by Le Questel, Jean-Yves; Laurence, Christian; Lachkar, Abdeljalil; Helbert, Maryvonne; Berthelot, Michel


Book ID
111972487
Publisher
Royal Society of Chemistry
Year
1992
Tongue
English
Weight
412 KB
Volume
12
Category
Article
ISSN
1472-779X

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A new procedure for protecting the amide, lactam, urea, and carbamate NH group with a triphenylmethyl (Tr) group is described. The utility of this method is illustrated with molecules that contain other functional groups. A mild deprotection using trifluoroacetic acid makes this a useful method for