Selective synthesis of 3-isochromanones
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Eiji Yoneda; Takayuki Kaneko; Shi-Wei Zhang; Shigetoshi Takahashi
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Article
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1998
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Elsevier Science
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French
β 233 KB
Rhodium-catalyzed cyclic carbonylation of 2-ethynylbenzylalcohols 1. under water-gas shift reaction conditions gives selectively 3.isochromanones 2 which are derived from 1 and one molecule each of hydrogen and carbon monoxide with incorporation of the hydroxymethyl group adjacent to the ethynyl gro