Hydrochlorothiazide N,N-dimethylacetamide disolvate
✍ Scribed by Johnston, Andrea ;Florence, Alastair J. ;Kennedy, Alan R.
- Publisher
- International Union of Crystallography
- Year
- 2006
- Tongue
- English
- Weight
- 314 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
Hydrochlorothiazide forms a 1:2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro-3,4-dihydro-2__H__-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethylacetamide disolvate), C~7~H~8~ClN~3~O~4~S~2~·2C~4~H~9~NO. The compound crystallizes with one hydrochorothiazide and two disordered solvent molecules in the asymmetric unit, with a hydrogen-bonding network comprising four N—H...O contacts.
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