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Hydro­chloro­thia­zide N,N-dimethyl­acetamide disolvate

✍ Scribed by Johnston, Andrea ;Florence, Alastair J. ;Kennedy, Alan R.


Publisher
International Union of Crystallography
Year
2006
Tongue
English
Weight
314 KB
Volume
62
Category
Article
ISSN
1600-5368

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✦ Synopsis


Hydrochlorothiazide forms a 1:2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro-3,4-dihydro-2__H__-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethylacetamide disolvate), C~7~H~8~ClN~3~O~4~S~2~·2C~4~H~9~NO. The compound crystallizes with one hydrochorothiazide and two disordered solvent molecules in the asymmetric unit, with a hydrogen-bonding network comprising four N—H...O contacts.


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