Synthesis of (9Z,12Z,15E)- and (9E,12Z,1
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Thierry Eynard; Jean-Michel Vatèle; Didier Poullain; Jean-Pierre Noël; Jean-Mich
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Article
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1994
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Elsevier Science
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English
β 743 KB
In order to study the effect of the double bonds geometry of linolenic acid (18:3 n-3) on its biological activities, (gz,12Z, I 5E)-and (9E, I 2Z, 15Z)-octadecatrienoic acids, found in many refined vegetable oils, were made by total synthesis. Synthesis of 18:3 A9c, 12c, 1St involves a Wittig reacti