HYBP_PSSP: a hybrid back propagation method for predicting protein secondary structure
β Scribed by Wu Qu; Bingru Yang; Wei Jiang; Lijun Wang
- Book ID
- 106175728
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 878 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0941-0643
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A novel computerized program has been developed for predicting the secondary structure of proteins from their amino acid sequences. The scheme of the Chou and Fasman method (1978, Adv. Enzymol. Relat. Subj. Biochem. 47,45-148) is closely followed. Some of their qualitative rules have been converted
A simple technique for identifying protein secondary structures through the analysis of backbone 13C chemical shifts is described. It is based on the Chemical-Shift Index [Wishart et al. (1992) Biochemistry, 31, 1647-1651] which was originally developed for the analysis of 1H(alpha) chemical shifts.
## Abstract A mathematical model is developed adequately describing an unfolded polypeptide chain without longβrange interactions in which fluctuating hydrogenβbonded Ξ±βhelices, Ξ²βbends, fragments of helices 3~10~, and other local structures are formed. The obtained model is a modification of a one