Huntingtin phosphorylation and signaling pathways that regulate toxicity in Huntington's disease
✍ Scribed by Sandrine Humbert; Frédéric Saudou
- Book ID
- 114414367
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 170 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1566-2772
No coin nor oath required. For personal study only.
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## Abstract Activating the ERK pathway (extracellular signal‐regulated kinase pathway) has proven beneficial in several models of Huntington's disease (HD), and drugs that are protective in HD models have recently been found to activate ERK. Thus, the ERK cascade may be a potential target for thera