✦ LIBER ✦

The IGF-1/Akt Pathway Is Neuroprotective in Huntington's Disease and Involves Huntingtin Phosphorylation by Akt

✍ Scribed by Sandrine Humbert; Elzbieta A. Bryson; Fabrice P. Cordelières; Nathan C. Connors; Sandeep R. Datta; Steven Finkbeiner; Michael E. Greenberg; Frédéric Saudou

Book ID: 117795197
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 300 KB
Volume: 2
Category: Article
ISSN: 1534-5807
DOI: 10.1016/s1534-5807(02)00188-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Insulin-like growth factor-1 (IGF-1) ind

Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells

✍ Wen-Hua Zheng; Rémi Quirion 📂 Article 📅 2006 🏛 BioMed Central 🌐 English ⚖ 913 KB

Hypoxia-induced iNOS expression in micro

Hypoxia-induced iNOS expression in microglia is regulated by the PI3-kinase/Akt/mTOR signaling pathway and activation of hypoxia inducible factor-1α

✍ Dah-Yuu Lu; Houng-Chi Liou; Chih-Hsin Tang; Wen-Mei Fu 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 456 KB

Insulin-like growth factor-1-dependent m

Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase–Akt pathway is inhibited by C2-ceramide in CAD cells

✍ Gonzalo Arboleda; Tze-Jen Huang; Catherine Waters; Alex Verkhratsky; Paul Fernyh 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 761 KB

Neuroprotective effect of guanosine agai

Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition

✍ Simone Molz; Tharine Dal-Cim; Josiane Budni; M.D. Martín-de-Saavedra; Javier Ege 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB 👁 2 views

## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re