Hunger sensation in patients with compensated and uncompensated type 1 and type 2 Diabetes Mellitus

✍ Scribed by Cugini, Pietro ;Fatati, Giuseppe ;Paggi, Anna ;Coaccioli, Stefano ;Paci, Francesca ;Palazzi, Mariangela ;Puxeddu, Adolfo

• Publisher: Wiley (John Wiley & Sons)
• Year: 1996
• Tongue: English
• Weight: 772 KB
• Volume: 20
• Category: Article
• ISSN: 0276-3478
• DOI: 10.1002/(sici)1098-108x(199607)20:1<85::aid-eat10>3.0.co;2-i

✦ Synopsis

Objective:

Diabetic patients (dp) refer increased hunger sensation (hs) when hyperglycemic but not yet ketogenic. as hs shows a within-day (ultradian cyclicity) and intra-day (circadian cyclicity) repetitivity, its recursive pattern was investigated in patients with type 1 and type 2 diabetes mellitus (dm), in compensated and uncompensated metabolic stage.

Method:

Hs was approached in its cyclic structure by means of spectral analysis (sa), and in its circadian rhythmicity by means of single cosinor analysis (sca), applied to self-rated scores of hs given every 30 min to their hs (orexigram) by dp.

Results:

Exaggerated periprandial, interprandial, and/or nocturnal peaks of hs were seen in the orexigram of both the type i and type ii dp. specific alterations in hs periodogram were detected, structurally denoting a relative prevalence of the ultradian components along with the deamplification and loss of the circadian harmonics.

Discussion:

The increase of hs (hyperorexia) in nonketotic dm may be formally attributed to a mechanism of frequency multiplication and amplitude demodulation in the multifrequency bioperiodic structure which physiologically regulates the recursive pattern to the daily hs in human beings.