𝔖 Bobbio Scriptorium
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Humoral Pathogenesis of Myasthenia Grayis

✍ Scribed by DANIEL B. DRACHMAN; SHARI DE SILVA; DAVID RAMSAY; ALAN PESTRONK

Book ID
119860644
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
913 KB
Volume
505
Category
Article
ISSN
0890-6564

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Myasthenia gravis (MG) and its animal model experimental autoimmune myasthenia gravis (EAMG) are caused by autoantibodies against nicotinic acetylcholine receptor (AChR) in skeletal muscle. The production of anti-AChR antibodies is mediated by cytokines produced by CD4+ and CD8+ T helper (Th) cells.