Interferon lambda 1 (IFN-k1) is a type III IFN that produces intracellular responses similar to those of IFN-a but in fewer cell types because of differences in the receptor distribution pattern, and this could potentially result in an improved safety profile. This was an open-label three-part study
Humoral immunity to immunodominant epitopes of Hepatitis C virus in individuals infected with genotypes 1a or 1b
✍ Scribed by Maria P Carlos; Yasuhiro Yamamura; Quynh Vu; Kendra Conzen; David E Anderson; José V Torres
- Book ID
- 116366120
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 187 KB
- Volume
- 111
- Category
- Article
- ISSN
- 1090-2341
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Previous studies from Japan have described an association between a conserved sequence within the hepatitis C virus (HCV) genome and resistance to interferon (IFN) therapy for patients infected with HCV genotype 1b [
Human leukocyte antigen B27 (HLA-B27) is associated with protection in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. This protective role is linked to single immunodominant HLA-B27-restricted CD8+ T-cell epitopes in both infections. In order to define the relative contrib