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Human–SCID mouse chimeric models for the evaluation of anti-cancer therapies

✍ Scribed by Richard B Bankert; Nejat K Egilmez; Stephen D Hess

Book ID
117786934
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
172 KB
Volume
22
Category
Article
ISSN
1471-4906

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## Abstract We have critically examined the nude mouse model for human retinoblastoma to determine whether or not characteristics found in the parent tumor are retained in the mouse. We have demonstrated that most tumors grown in the anterior chamber of the nude mouse maintain a similar karyotype,