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A human-SCID-mouse-islet transplant model for the evaluation of the regulatory activity of donor bone marrow cells

✍ Scribed by James M. Mathew; Silvia Alvarez; Teresa Vallone; Bonnie B. Blomberg; Miller Joshua; Violet Esquenazi


Book ID
116529932
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
23 KB
Volume
64
Category
Article
ISSN
0198-8859

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## Abstract ## Background Fabry disease (FD) is a lysosomal storage disorders characterized by a deficiency of the lysosomal enzyme, α‐galactosidase A. This results in the accumulation of glycolipids, mainly globotriaosylceramide (GL‐3), in the lysosomes of various organs. Although bone marrow tra