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Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment

โœ Scribed by J.L.C.M. Dorne; K. Walton; A.G. Renwick


Book ID
116461136
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
969 KB
Volume
42
Category
Article
ISSN
0278-6915

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## Abstract Hepatic metabolism and renal excretion constitute the main routes of xenobiotic elimination in humans. Improving human risk assessment for threshold contaminants requires the incorporation of quantitative data related to their elimination (toxicokinetics) and potential toxic effects (to