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Human T cell response to myelin basic protein: Is the T cell repertoire different in multiple sclerosis patients and healthy subjects?

✍ Scribed by E. Tournier-Lasserve; G.A. Hashim; M.A. Bach

Book ID
119107129
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
57 KB
Volume
16
Category
Article
ISSN
0165-5728

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πŸ“œ SIMILAR VOLUMES

Human T-cell response to myelin basic pr
Human T-cell response to myelin basic protein in multiple sclerosis patients and healthy subjects
✍ E. Tournier-Lasserve; G. A. Hashim; Dr. M. A. Bach πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 712 KB

In order to explore the T-cell repertoire to myelin basic protein (BP) of both multiple sclerosis (MS) patients and healthy subjects (HS), we raised BP reactive T-cell lines from blood mononuclear cells of eight MS patients and five HS. These lines were triggered in vitro by human BP. When analyzing

T cell response to myelin basic protein
T cell response to myelin basic protein epitopes in multiple sclerosis patients and healthy subjects
✍ Roland Liblau; Elisabeth Tournier-Lasserve; Jacqueline Maciazek; GΓ©rad Dumas; Od πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 388 KB

T cell lines and clones specific for human myelin basic protein (BP) were selected from three multiple sclerosis (MS) patients and two healthy subjects and tested for their proliferative responses to a battery of synthetic peptides, 9 to 21 amino acid residues long. The combined amino acid sequence