N-Monoalkyl and N,N-dialkyl carbamate prodrugs of naltrexone (NTX), an opioid antagonist, were synthesized and their in vitro permeation across human skin was determined. Relevant physicochemical properties were also determined. Most prodrugs exhibited lower melting points, lower aqueous solubilitie
โฆ LIBER โฆ
Human Skin Permeation of Branched-Chain 3-O-Alkyl Ester and Carbonate Prodrugs of Naltrexone
โ Scribed by Haranath K. Vaddi; Mohamed O. Hamad; Jianhong Chen; Stan L. Banks; Peter A. Crooks; Audra L. Stinchcomb
- Book ID
- 106492550
- Publisher
- Springer US
- Year
- 2005
- Tongue
- English
- Weight
- 168 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0724-8741
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