## Abstract To determine the function of biomaterials on osteoblasts, we studied the effects of two different biomaterials, sintered bovine bone (true bone ceramic) and hydroxyapatite‐related material, on DNA and collagen synthesis and osteoblastic expression in osteoblast‐like cells __in vitro__.
✦ LIBER ✦
Human skeletal growth factor stimulates collagen synthesis and inhibits proliferation in a clonal osteoblast cell line (MC3T3-E1)
✍ Scribed by Susan Linkhart; Subburaman Mohan; Thomas A. Linkhart; Masayoshi Kumegawa; David J. Baylink
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 933 KB
- Volume
- 128
- Category
- Article
- ISSN
- 0021-9541
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## Abstract We examined the relationship between signal transduction and the expression of insulin‐like growth factor I (IGF‐I), IGF‐I receptor level, and IGF binding proteins (IGFBPs) in murine clonal osteoblastic MC3T3‐E1 cells. 12–O‐Tetradecanoylphorbol‐13‐acetate (TPA), an activator of protein