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Human red cell glyoxalase I polymorphism

✍ Scribed by C. W. Parr; I. A. Bagster; S. G. Welch

Publisher
Springer
Year
1977
Tongue
English
Weight
258 KB
Volume
15
Category
Article
ISSN
0006-2928

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✦ Synopsis

Human erythrocyte glyoxalase I has been subjected to starch gel electrophoresis, and its isoenzymatic forms have been visualized by a new positive staining procedure. The enzyme exhibits polymorphism and holds promise as a useful new genetic marker.

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Glyoxalase polymorphism has been studied in 7296 persons from populations in South Asia, Southeast Asia, Oceania, Iran and Colombia. The GLO frequencies are very low in most of Oceania, including Australia, somewhat higher in Southeast Asia, and intermediate though variable in India. In Iran the GLO

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✍ J. KΓΆmpf; S. Bissbort; S. Gussmann; H. Ritter πŸ“‚ Article πŸ“… 1975 πŸ› Springer 🌐 English βš– 151 KB

The polymorphism of glyoxalase I was investigated in 169 mother-child combinations from southwestern Germany. Glyoxalase I (GLO) has 3 common phenotypes: GLO 1, GLO 2-1, and GLO 2. The results are in good agreement with the formal hypothesis: Two alleles GLO1 and GLO2 at an autosomal locus. The GLO1