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Human papillomavirus type 16 E6 gene variations in Chinese population

โœ Scribed by H.B. Cai; C.C. Chen; X.H. Ding

Book ID
116443738
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
113 KB
Volume
36
Category
Article
ISSN
0748-7983

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## Abstract The p53 tumor suppressor pathway is disrupted by human papillomavirus (HPV) in most cervical cancer cells. The E6 proteins, which could mediate p53 degradation, are related to cellular immortalization, transformation, and tumor formation. In order to study the E6 abrogated p53 function