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Human Papillomavirus Infection in Squamous Cell Carcinoma of the Vulva, in Various Synchronous Epithelial Changes and in Normal Vulvar Skin

✍ Scribed by Marjolein J. Kagie; Gemma G. Kenter; Yvonne Zomerdijk-Nooijen; Jo Hermans; Ed Schuuring; Petra J. Timmers; J.Baptist Trimbos; Gert-Jan Fleuren

Book ID
112247218
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
86 KB
Volume
67
Category
Article
ISSN
0090-8258

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Human papillomavirus in vulvar squamous-
Human papillomavirus in vulvar squamous-cell carcinoma and in normal vulvar tissues: A search for a possible impact of HPV on vulvar cancer prognosis
✍ Ulla HΓΈrding; Johannes E. Bock; Birgitte Kringsholm; Benny Andreasson; Jakob Vis πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 French βš– 460 KB

## Abstract Paraffin‐embedded sections of vulvar squamous‐cell carcinomas and of normal vulvar tissues were examined for HPV types 6, 11, 16, 18 and 33 by the polymerase chain reaction. Overall, 19 of 62 tumours harboured HPV DNA of types 16, 18 or 33. HPV types 6 and 11 were not detected. HPV DNA

p53 protein overexpression is common and
p53 protein overexpression is common and independent of human papillomavirus infection in squamous cell carcinoma of the vulva
✍ Marjolein J. Kagie; Gemma G. Kenter; Rob A.Β E.Β M. Tollenaar; Jo Hermans; J. Bapt πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 85 KB πŸ‘ 2 views

## RESULTS. DO7, an anti-p53 monoclonal antibody, showed p53 overexpression in 35 carcinomas (53%). Consensus primer PCR showed HPV infection in 12 carcinomas