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Human mast cells express intracellular TRAIL

✍ Scribed by Beata Berent-Maoz; Souzan Salemi; David Mankuta; Hans-Uwe Simon; Francesca Levi-Schaffer

Book ID
113527261
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
394 KB
Volume
262
Category
Article
ISSN
0008-8749

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Stem cell factor (SCF) is a major cytokine regulator of mast cell growth and function. The present study demonstrates that human mast cells are able to produce SCF. Constitutive synthesis of SCF mRNA was seen in the mast cells isolated from human lung and skin by RT-PCR. This was confirmed by in sit