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Human major histocompatibility complex sequenced

✍ Scribed by Jane Bradbury

Book ID
117313268
Publisher
The Lancet
Year
1999
Tongue
English
Weight
24 KB
Volume
354
Category
Article
ISSN
0140-6736

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Mutants that had lost expression of alleles of one or more HLA loci were isolated with immunoselection after gamma-irradiation of a human lymphoblastoid cell line LCL 721. DNAs from the mutants were digested with restriction endonucleases and analyzed by Southern blotting using probes for class I HL