Complete sequence and gene map of a human major histocompatibility complex
โ Scribed by The MHC sequencing consortium,
- Book ID
- 109815528
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 114 KB
- Volume
- 401
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/44853
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Mutants that had lost expression of alleles of one or more HLA loci were isolated with immunoselection after gamma-irradiation of a human lymphoblastoid cell line LCL 721. DNAs from the mutants were digested with restriction endonucleases and analyzed by Southern blotting using probes for class I HL
The human major histocompatibility complex (MHC), on the short arm of chromosome 6, represents one of the most extensively characterised regions of the human genome. This -4 Mb segment of DNA contains genes encoding the polymorphic MHC class I and class I1 molecules which are involved in antigen pre