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Human high-affinity FcγRI (CD64) gene mapped to chromosome 1q21.2-q21.3 by fluorescence in situ hybridization

✍ Scribed by S. Takai; M. Kasama; K. Yamada; N. Kai; N. Hirayama; H. Namiki; T. Taniyama


Publisher
Springer
Year
1994
Tongue
English
Weight
702 KB
Volume
93
Category
Article
ISSN
0340-6717

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FcyRI is an interferon inducible high-affinity receptor for IgG which is important in antibody dependent killing, the binding of immune complexes and internalization of antibody-coated particles (Unkless et al. 1988;Ravetch and Kinet 1991). Biochemical characterization of FcyRI indicates that it is