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Human herpesvirus 8-encoded interleukin-6 homologue (viral IL-6) induces endogenous human IL-6 secretion

✍ Scribed by Yasuko Mori; Norihiro Nishimoto; Mika Ohno; Reiko Inagi; Panadda Dhepakson; Kiyoko Amou; Kazuyuki Yoshizaki; Koichi Yamanishi

Book ID
101320092
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
171 KB
Volume
61
Category
Article
ISSN
0146-6615

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The infectivity of human herpesvirus 6 (HHV-6) in a human hepatoma cell line, Hep G2 cells, and the effect of HHV-6 on production of inflammatory cytokines in these cells were examined to analyze pathogenesis of HHV-6 in the liver. We demonstrated that Hep G2 cells were susceptible to infection with