Human herpesvirus 8: Biology and role in the pathogenesis of Kaposi’s sarcoma and other aids-related malignancies
✍ Scribed by Abel Viejo-Borbolla; Matthias Ottinger; Thomas F. Schulz
- Book ID
- 107540597
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 532 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1548-3568
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## Skin biopsy sections of Kaposi's sarcoma (KS) from 25 patients (5 AIDS-related, 20 classical cases) were histologically staged and hybridized in situ with oligonucleotide probes for constitutively transcribed human herpesvirus 8 (HHV-8) mRNA T0.7 and T1.1 using a colourimetric technique. T1.1 i
## Abstract We report the molecular characterization of 38 new Kaposi's sarcoma‐associated herpesvirus (KSHV) strains from Russian patients with either classic (25 cases), epidemic/AIDS‐associated (7 cases), or posttransplant/immunosuppressed patients (6 cases), or Kaposi's sarcoma (KS). While a co
Kaposi's sarcoma (KS) is a malignancy suspected of having an infectious etiology. Unique viral DNA sequences were recognized in KS lesions, using a novel technique that identifies small differences between two complex genomes. The virus had homology with the herpesvirus family, especially Epstein Ba