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Human Hepatic Microsomal Epoxide Hydrolase: Comparative Analysis of Polymorphic Expression

✍ Scribed by Christopher Hassett; Jing Lin; Cara L. Carty; Elizabeth M. Laurenzana; Curtis J. Omiecinski

Book ID
115566431
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
711 KB
Volume
337
Category
Article
ISSN
0003-9861

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Microsomal epoxide hydrolase (mEH) is inducible by a number of xenobiotics. Induction of mEH by certain chemopreventive agents may implicate the protective effect. In contrast, many of carcinogenic agents also induce the enzyme. The hepatotoxicity and mEH expression by methylthiazoles, which are inc