Human genetics: the basics

✍ Scribed by Lewis, Ricki

• Publisher: Routledge
• Year: 2017
• Tongue: English
• Leaves: 207
• Series: Basics (Routledge (Firm))
• Edition: Second edition
• Category: Library

✦ Synopsis

"This thoroughly updated new edition of Human Genetics: The Basics provides a concise background of gene structure and function through the lens of real examples, from families living with inherited diseases to population-wide efforts in which millions of average people are learning about their genetic selves. The book raises compelling issues concerning: The role of genes in maintaining health and explaining sickness. Genetic testing, gene therapy, and genome editing. The common ancestry of all humanity and how we are affecting our future. Written in an engaging, narrative manner, this concise introduction is an ideal starting point for anyone who wants to know more about genes, DNA, genomes, and the genetic ties that bind us all.";1. From Mendel's peas to double helices -- 2. How genes work -- 3. Genes and health -- 4. Genetic testing -- 5. Gene therapy and genome editing -- 6. From ancestry to destiny.

✦ Table of Contents

Cover......Page 1
Half Title......Page 2
Title Page......Page 4
Copyright Page......Page 5
Table of Contents......Page 6
List of figures......Page 8
List of tables......Page 10
Acknowledgements......Page 11
List of Abbreviations......Page 13
From Genes to Genomes......Page 16
Agriculture is Applied Genetics......Page 19
Mendel’s Experiments—The Mystery of the MissingTraits......Page 21
The Chromosome Connection......Page 29
In Pursuit of the Genetic Material......Page 35
2 How Genes Work......Page 53
A Brief History of CF......Page 54
Mikayla’s Story......Page 57
The Individual Level: Tissues and Organs......Page 65
The Family Level......Page 69
The Population......Page 73
A Genomic View of Health......Page 81
Causes of Death—An Organizing Framework......Page 84
Cancer: The Cell Cycle Out of Control......Page 93
4 Genetic Testing......Page 114
The First Generation of Genetic Tests: Proteins......Page 115
The Second Generation of Genetic Tests: DNA......Page 129
The Third Generation of Genetic Tests: Exomes andGenomes......Page 134
5 Gene Therapy and Genome Editing......Page 139
Gene Therapy......Page 141
Gene and Genome Editing......Page 149
DNA as Clock and Compass......Page 162
The First Hominins......Page 167
DNA Evidence Overlaps Fossil Evidence......Page 169
Expansion Out of Africa......Page 171
From Archaic Humans to Modern Humans......Page 173
Into Europe......Page 178
Genetic Genealogy and Ancestry Testing......Page 184
The Future: Will Humanity Homogenize or Diverge?......Page 185
Glossary......Page 190
Bibliography......Page 195
Index......Page 204

✦ Subjects

Genetics, Medical;HEALTH & FITNESS--Diseases--General;Human genetics;MEDICAL--Clinical Medicine;MEDICAL--Diseases;MEDICAL--Evidence-Based Medicine;MEDICAL--Internal Medicine;Electronic books;Popular works;Human genetics -- Popular works;HEALTH & FITNESS -- Diseases -- General;MEDICAL -- Clinical Medicine;MEDICAL -- Diseases;MEDICAL -- Evidence-Based Medicine;MEDICAL -- Internal Medicine