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Human FOXP3+ Regulatory T Cells in Transplantation

✍ Scribed by P. Boros; J. S. Bromberg

Book ID: 114805201
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 78 KB
Volume: 9
Category: Article
ISSN: 1600-6135
DOI: 10.1111/j.1600-6143.2009.02704.x

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## Abstract The transcription factor FOXP3 is critical for development and function of regulatory T cells (Treg). Their number and functioning appears to be crucial in the prevention of autoimmunity and allergy, but also to be a negative prognostic marker for various solid tumors. Although expressi