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FOXP3+ regulatory T cells as biomarkers in human malignancies

✍ Scribed by Bignone, Paola A; Banham, Alison H

Book ID
115503175
Publisher
Informa plc
Year
2008
Tongue
English
Weight
465 KB
Volume
8
Category
Article
ISSN
5847-4714

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## Abstract The transcription factor FOXP3 is critical for development and function of regulatory T cells (Treg). Their number and functioning appears to be crucial in the prevention of autoimmunity and allergy, but also to be a negative prognostic marker for various solid tumors. Although expressi