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Human chromosomal banding by in situ hybridization of isochores

✍ Scribed by Salvatore Saccone; Giorgio Bernardi


Book ID
110319724
Publisher
Springer
Year
2001
Tongue
English
Weight
411 KB
Volume
23
Category
Article
ISSN
1573-0603

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Recombinant lambda bacteriophage clone H3 containing a human DNA segment of 14.9 kb present in one or two copies per haploid genome was isolated. In situ hybridization to human metaphase chromosomes of the 3H-labeled cloned DNA resulted in highly significant labeling (53% of cells) of band p36 of ch