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Human CD8+ cell non-cytolytic anti-HIV activity mediated by a novel cytokine

✍ Scribed by Blackbourn, D.J.; Mackewicz, C.; Barker, E.; Levy, J.A.

Book ID
122368697
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
532 KB
Volume
145
Category
Article
ISSN
0923-2494

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## Abstract Treatment with anti‐CD3 mAb modulates immune responses that cause type 1 diabetes and other diseases. CD8^+^ Tregs can be induced in vitro and in vivo by mAb. However, 1/3 of patients do not respond to drug therapy and in an equal proportion, anti‐CD3 mAb does not induce Tregs in vitro.