Human Calmodulin-Like Protein (CLP) Expression in Oral Squamous Mucosa and in Malignant Transformation
β Scribed by Michael D. Brooks; Richard D. Bennett; Emanuel E. Strehler; Thomas J. Sebo; Stephen E. Eckert; Alan B. Carr
- Book ID
- 109135407
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 392 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1059-941X
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Epithelial dysplasia is usually used to establish the prognosis of oral premalignant lesions. Its assessment, however, is subjective and does not always correctly predict the outcome of the lesions in terms of malignant transformation. Early molecular alteration(s) that dictate the development of ca
## Abstract ## Background Increased cytoplasmic HuR expression has been noted in several cancer types, where it may contribute to the increased cyclooxygenaseβ2 (COXβ2) expression observed during tumorigenesis and metastasis. ## Methods To assess the correlation between COXβ2 and HuR in oral squ