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Human ARF binds E2F1 and inhibits its transcriptional activity

✍ Scribed by Eymin, Béatrice; Karayan, Lucie; Séité, Paule; Brambilla, Christian; Brambilla, Elisabeth; Larsen, Christian-Jacques; Gazzéri, Sylvie


Book ID
110064515
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
239 KB
Volume
20
Category
Article
ISSN
0950-9232

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E2F1 inhibition of transcription activat
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Cellular transcription factor E2F1 is thought to regulate the expression of genes important for cell cycle progression and cell proliferation. Deregulated E2F1 expression induces S-phase entry in quiescent cells and inhibits myogenic differentiation. We show here that E2F1 inhibits the activation of