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Association of Purα and E2F-1 suppresses transcriptional activity of E2F-1

✍ Scribed by Darbinian, Nune; Gallia, Gary L; Kundu, Mondira; Shcherbik, Natalia; Tretiakova, Anna; Giordano, Antonio; Khalili, Kamel


Book ID
110062399
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
332 KB
Volume
18
Category
Article
ISSN
0950-9232

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Regulation of the Pur-alpha promoter by
✍ Nune Darbinian; Martyn K. White; Kamel Khalili 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB

Pura is a ubiquitously expressed multifunctional nucleic acid-binding protein that is involved in many cellular processes including transcriptional regulation, the cell cycle, oncogenic transformation, and post-natal brain development. Previously, Pura protein was found to bind to E2F-1, inhibit E2F