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Human antithrombin III-derived heparin-binding peptide, a novel heparin antagonist

✍ Scribed by Satomi Onoue; Yoshitaka Nemoto; Sunao Harada; Takehiko Yajima; Kazuhisa Kashimoto

Book ID: 117174365
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 586 KB
Volume: 73
Category: Article
ISSN: 0024-3205
DOI: 10.1016/s0024-3205(03)00705-7

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## Abstract The serine proteinase inhibitor antithrombin III (ATIII) is a key regulatory protein of intrinsic blood coagulation. ATIII attains its full biological activity only upon binding polysulfated oligosaccharides, such as heparin. A series of synthetic peptides have been prepared based on th