Binding of heparin to human antithrombin III as studied by measurements of tryptophan fluorescence
β Scribed by Roland Einarsson; Lars-Olov Andersson
- Book ID
- 113125449
- Publisher
- Elsevier Science
- Year
- 1977
- Weight
- 449 KB
- Volume
- 490
- Category
- Article
- ISSN
- 0005-2795
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
1H NMR and 13C NMR relaxation measurements at different magnetic field strengths were used to study the nature of overall and internal motions, in aqueous solution, of the synthetic pentasaccharide (A-G-A\*-I-A M) corresponding to the binding site of heparin for antithrombin III. Two-dimensional dou
Binding of a synthetic, high-affinity heparin pentasaccharide and of intact heparin to both native and elastase-modified human antithrombin III have been examined by 'H-n.m.r. spectroscopy. The pentasaccharide perturbs many protein resonances in the same way as does intact heparin. There are, howeve