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Human antibodies responsible for binding inhibition and polymerization inhibition of human immunodeficiency virus type 1 reverse transcriptase

✍ Scribed by Fumitomo Odawara; Kouichi Sano; Toru Otake; Susumu Okubo; Takashi Nakano; Tomohiko Takasaki; Noboru Ueba; Hideo Misaki; Masuyo Nakai

Book ID
114051645
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
933 KB
Volume
199
Category
Article
ISSN
0022-1759

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Recombinant human antibodies against the
Recombinant human antibodies against the reverse transcriptase of human immunodeficiency virus type-1
✍ Alon Herschhorn; Arie Admon; Amnon Hizi πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 645 KB

Inhibitory antibodies to the reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) can be used to block the life cycle of the virus. We have isolated five different human single chain Fv (ScFv) antibodies specific for HIV-1 RT from an antibody phage display library. Three of thes