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HTLV-I ASSOCIATED MYELOPATHY, A NEW CLINICAL ENTITY

✍ Scribed by Osame, Mitsuhiro; Usuku, Koichiro; Izumo, Shuji; Ijichi, Naomi; Amitani, Hiroyoko; Igata, Akihiro; Matsumoto, Makoto; Tara, Mitsutoshi

Book ID
122643648
Publisher
The Lancet
Year
1986
Tongue
English
Weight
346 KB
Volume
327
Category
Article
ISSN
0140-6736

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To estimate the replication of the human T-cell leukemia virus type I (HTLV-I) in patients with HTLV-I-associated myelopathy (HAM), or tropical spastic paraparesis (TSP), HTLV-I DNA integrated into lymphocyte genomes was analyzed by Southern blot hybridization. HTLV-I DNA was detected in 125 (82%) o