𝔖 Bobbio Scriptorium
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How αβ T-cell receptors ‘see’ peptide/MHC complexes

✍ Scribed by Yueh-hsiu Chien; Mark M. Davis


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
768 KB
Volume
14
Category
Article
ISSN
0167-5699

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Fate of intercellular MHC–peptide–T-cell
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Antigen-specific T-cell activation requires the formation of a transient cell-cell conjugate between a T cell and an appropriate antigen presenting cell (APC). Focal aggregation of T-cell receptor (TCR) molecules at the T-cell-APC membrane interface accompanies formation of multiple non-covalent int