Fate of intercellular MHC–peptide–T-cell
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Brian R. Clark
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Article
📅
1995
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John Wiley and Sons
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English
⚖ 375 KB
Antigen-specific T-cell activation requires the formation of a transient cell-cell conjugate between a T cell and an appropriate antigen presenting cell (APC). Focal aggregation of T-cell receptor (TCR) molecules at the T-cell-APC membrane interface accompanies formation of multiple non-covalent int