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How variable is an spontaneous mutation rate in cultured mammalian cells?

✍ Scribed by Jan J.B. Boesen; Matthieu J. Niericker; Nicole Dieteren; Jo W.I.M. Simons


Book ID
113194694
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
623 KB
Volume
307
Category
Article
ISSN
0027-5107

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Spontaneous mutation rate to thioguanine
✍ John Morrow; Douglas Stocco; Emily Barron πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 358 KB

## Abstract The mutation rate to thioguanine resistance was 3.11 Γ— 10^βˆ’6^ in a near diploid V79 hamster cell line and 7.58 Γ— 10^βˆ’8^ in a near tetraploid derivative produced with colchicine. The specific activities of glucose‐6‐phosphate dehydrogenase and phosphoglycerate kinase of the tetraploid li