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How the Bcl-2 family of proteins interact to regulate apoptosis

✍ Scribed by van Delft, Mark F; Huang, David CS


Book ID
110020731
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
511 KB
Volume
16
Category
Article
ISSN
0007-0610

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## Abstract Bcl‐2 family members are the arbiters of mitochondrial apoptotic pathway, which is conserved through evolution. The stoichiometry of pro‐ versus antiapoptotic Bcl‐2 family members in the cell determines whether the cell lives or dies. This fine balance is regulated at the transcriptiona