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How many JAK inhibitors in myelofibrosis?

✍ Scribed by Ferreira, Bruna Velosa; Harrison, Claire


Book ID
126984808
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
247 KB
Volume
27
Category
Article
ISSN
1521-6926

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Hypothesis: How do JAK2-inhibitors work
✍ Ruben Mesa; Robert Peter Gale πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 English βš– 205 KB

JAK2-inhibitors rapidly reduce spleen enlargement and clinical symptoms in persons with myelofibrosis but have little, if any, effect on the WBC, anemia, decreased platelets or bone marrow fibrosis. Also, JAK2-inhibitors are active in persons with and without the JAK2-mutation. Based on these and ot